There are four changes to the starting side that was narrowly beaten by Australia last weekend, as Ollie Sleightholme, Jack van Poortvliet, Freddie Steward, and Sam Underhill all come into the team.

Jamie George will captain England, once again supported by four vice-captains: Maro Itoje, Ben Earl, Ellis Genge, and George Ford. Wing Tom Roebuck is included among the replacements for the first time this autumn.

“We're excited to challenge ourselves against the world's top-ranked team and back-to-back Rugby World Cup champions,” said Borthwick. “Test matches against South Africa are always thrilling contests, and I'm sure Saturday will be no exception.”